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Plasma Cell Marker
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Plasma Cell Marker
Plasma Cell Marker
Plasma Cell Marker from MyBioSource.com
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Plasma Cell Marker
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MyBioSource.com's
Plasma Cell Marker
is a Mouse monoclonal antibody. It reacts with Human. This antibody has been shown to work in applications such as: Immunohistochemistry.
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Product Specs
Item
Plasma Cell Marker
Company
MyBioSource.com
Price
Pricing Info
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Catalog Number
MBS438191
Quantity
0.1 mg
Applications
Immunohistology (IH)
Conjugate/Tag
Unconjugated
Reactivity
Human
Target
Plasma Cell Marker
Isotype
IgG2a
Clone
LIV3G11; same as 7B18
Host
Mouse
Immunogen
It recognizes an intra-cytoplasmic antigen, which shows a very high degree of specificity for plasma cells. This antigen is present in normal as well as neoplastic plasma cells. Plasma cells, which are large lymphocytes derived from an antigen-specific B cell, secrete antibodies and are responsible for humoral immunity. Plasma cells differentiate from B cells upon stimulation by CD4+ lymphocytes. The B cell acts as an antigen-presenting cell (APC), consuming an offending pathogen, which is taken up by the B cell by phagocytosis and broken down within proteosomes. Plasma cells contain basophilic cytoplasm; their nucleus contains heterochromatin organized in a characteristic cartwheel arrangement. This MAb superbly recognizes normal and neoplastic plasma cells in routine formalin-fixed, paraffin-embedded tissue sections. It is of potential value in identifying myeloma or plasmacytoma in bone marrow or other tissues. It also helps differentiate lympho-plasmacytoid lymphoma from lymphocytic and follicular lymphoma. Note that this MAb is not suitable for staining frozen tissues
Clonality
Monoclonal
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MyBioSource.com
P.O. Box 153308
San Diego
,
California
United States
Phone
: 1-888-627-0165 (toll free) or 1-858-633-0165
Fax: 1-858-633-0166
Email: sales@mybiosource.com
Company Profile
Website:
http://www.MyBioSource.com
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Plasma Cell Marker from MyBioSource.com
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